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Familial tumoral calcinosis: association with cerebral and peripheral aneurysm formation
W M Adams1, R D Laitt, M Davies
1Department of Neuroradiology, Central Manchester Healthcare Trust, UK.
Neuroradiology
|June 24, 1999
Abstract:
Two siblings with histologically and radiologically proven tumoral calcinosis presented with cerebral and peripheral aneurysms. The brother died of a ruptured subclavian artery aneurysm after surgical repair of brachial, iliofemoral and coeliac axis aneurysms. Magnetic resonance and catheter angiography in the sister demonstrated marked carotid dysplasia and a left ophthalmic segment aneurysm, not amenable to treatment. We believe this is the first reported case of familial aneurysms in association with tumoral calcinosis.