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Prenatal diagnosis of alobar holoprosencephaly at 10 weeks of gestation

C D Turner1, S Silva, P Jeanty

  • 1Department of Ultrasound, Women's Health Alliance, Nashville, TN 37203, USA.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
|June 25, 1999
PubMed

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...