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Related Experiment Videos

Tinea capitis: an overview with emphasis on management.

A K Gupta1, S L Hofstader, P Adam

  • 1Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada. agupta@execulink.com

Pediatric Dermatology
|June 26, 1999
PubMed
Summary

Newer antifungal medications like itraconazole, terbinafine, and fluconazole are effective and safe treatments for tinea capitis in children. These options offer a better benefit-risk ratio than older therapies, addressing changing fungal infection patterns.

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Area of Science:

  • Dermatology
  • Mycology
  • Pediatrics

Background:

  • Tinea capitis is a common pediatric fungal infection.
  • Epidemiological shifts in North America show *Trichophyton tonsurans* predominating over *Microsporum audouinii*.
  • This shift reduces the diagnostic utility of Wood's light as *T. tonsurans* infections are typically Wood's light negative.

Purpose of the Study:

  • To review the efficacy and safety of newer antifungal agents for treating tinea capitis.
  • To compare newer treatments with the long-standing griseofulvin therapy.
  • To provide information on treatment regimens for *T. tonsurans* and other endothrix species.

Main Methods:

  • Review of current literature on antifungal treatments for tinea capitis.
  • Analysis of treatment regimens including itraconazole, terbinafine, and fluconazole.

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  • Comparison of treatment durations and dosages for different fungal species.

    • Main Results:

    • Newer agents (itraconazole, terbinafine, fluconazole) demonstrate effectiveness and safety in treating tinea capitis.
    • Various dosing regimens (continuous, pulse) are effective for *T. tonsurans* infections.
    • Ectothrix infections may require longer treatment durations.

    Conclusions:

    • Newer antifungal agents offer a high benefit:risk ratio for tinea capitis treatment.
    • These agents may supersede griseofulvin, the traditional mainstay therapy.
    • Adjunctive measures and prevention of reinfection are important considerations.