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Novel approaches for discovering industrial enzymes
B Marrs1, S Delagrave, D Murphy
1Hercules Incorporated, Hercules Research Center, 500 Hercules Road, Wilmington, DE 19808, USA.
Current Opinion in Microbiology
|June 29, 1999
Abstract:
New technologies for enzyme discovery are changing the rules of the game for industrial biocatalysis. More kinds of enzymes are available, their hardiness is increasing, and their costs are coming down. These changes are the key drivers for a rebirth of interest in industrial applications of enzymes. The major enabling discovery approaches include screening of biodiversity, genomic sequencing, directed evolution and phage display.