Related Experiment Video

Updated: Oct 20, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

Clinical results of mitral valve repair by reconstructing artificial chordae tendineae in children

T Matsumoto1, H Kado, M Masuda

  • 1Department of Cardiovascular Surgery, Fukuoka Children's Hospital, and the Department of Cardiac Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

The Journal of Thoracic and Cardiovascular Surgery
|June 29, 1999
PubMed

Insights

Mitral valve repair using artificial chordae is safe and effective in children with mitral regurgitation. This technique shows excellent short-term results, with no complications or significant residual regurgitation in pediatric patients.

Area of Science:

  • Cardiovascular Surgery
  • Pediatric Cardiology
  • Biomaterials in Medicine

Background:

  • Growing use of expanded polytetrafluoroethylene (ePTFE) sutures for mitral valve repair in adults.
  • Limited data on the efficacy and safety of ePTFE chordal reconstruction in pediatric populations.

Purpose of the Study:

  • To evaluate the safety and effectiveness of mitral valve repair using artificial chordae in children.
  • To assess short-term outcomes and echocardiographic results in pediatric patients with mitral regurgitation.

Main Methods:

  • Retrospective study of 16 children (5 months–12.8 years) with moderate-to-severe mitral regurgitation undergoing artificial chordae repair.
  • Mitral valve repair involved ePTFE chordal reconstruction and Kay-Reed annuloplasty for annular dilatation.

Main Results:

  • No operative deaths or morbidity observed.
  • All patients had trivial or less mitral regurgitation post-surgery.
  • No valve-related events occurred during a median follow-up of 14.8 months.
  • Left ventricular dimensions normalized post-repair.

Conclusions:

  • Mitral valve repair with artificial chordae is a safe and effective procedure in infants and children.
  • The technique demonstrates promising short-term outcomes for pediatric mitral regurgitation.
Abstract

More Related Videos

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...