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Related Experiment Videos

Data collection in multi-center clinical trials via Internet. A generic system in Java.

H Sippel1, H P Eich, C Ohmann

  • 1Department of General and Trauma Surgery, Heinrich-Heine-University, Duesseldorf, Germany. sippel@uni-duesseldorf.de

Studies in Health Technology and Informatics
|June 29, 1999
PubMed
Summary

This study introduces a secure Java-based client/server system for clinical trial data collection, enhancing data quality and security over traditional HTML/CGI methods.

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Area of Science:

  • Computer Science
  • Medical Informatics
  • Software Engineering

Background:

  • Traditional internet data collection using HTML/CGI lacks robust security features.
  • Existing systems often compromise data integrity and quality.

Purpose of the Study:

  • To develop and present a secure, extensible Java-based client/server system for clinical trial data collection.
  • To enhance data quality through multi-lingual data dictionaries and GUI plausibility checks.
  • To compare the Java system's security and functionality against HTML/CGI approaches.

Main Methods:

  • Developed a three-tier client/server application using Java and TCP/IP.
  • Implemented a multi-lingual data dictionary for document creation.
  • Integrated GUI components with plausibility checking capabilities.

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  • Designed for extensibility across various clinical trial types.
  • Main Results:

    • The Java system offers enhanced security features compared to HTML/CGI.
    • Improved data quality is achieved through built-in plausibility checks.
    • The system architecture supports efficient handling and monitoring of client requests via an application server.

    Conclusions:

    • The developed Java system provides a secure and high-quality alternative for internet-based clinical trial data collection.
    • Its extensible design makes it suitable for diverse clinical trial applications.
    • Java's capabilities significantly improve upon the security limitations of HTML/CGI methods.