In silico predictions; in vivo veritas

Novel multiparameter correlates of Coxiella burnetii infection and vaccination identified by longitudinal deep immune profiling.

Scientific reports·2020

HLA- and genotype-based risk assessment model to identify infantile onset pompe disease patients at high-risk of developing significant anti-drug antibodies (ADA).

Clinical immunology (Orlando, Fla.)·2019

Can we prevent immunogenicity of human protein drugs?

Annals of the rheumatic diseases·2009

Clinical validation of the "in silico" prediction of immunogenicity of a human recombinant therapeutic protein.

Clinical immunology (Orlando, Fla.)·2007

Confirmation of immunogenic consensus sequence HIV-1 T-cell epitopes in Bamako, Mali and Providence, Rhode Island.

Human vaccines·2006

De-immunization of therapeutic proteins by T-cell epitope modification.

Developments in biologicals·2005

Bonsai reconstructs tree representations for distortion-free visualization and exploration of high-dimensional data.

Nature biotechnology·2026

Enhanced antitumor immunity of mRNA vaccines by bioorthogonal-like delayed activation of exogeneous STING.

Nature biotechnology·2026

A blinded, prospective benchmark of in silico antibody discovery anchored to experimental affinity and developability.

Nature biotechnology·2026

High-throughput synthesis of DNA fragments by molecular self-assembly of overlapping oligonucleotides.

Nature biotechnology·2026

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells.

Nature biotechnology·2026

Characterization of microbial dark matter at scale with MetaSBT and taxonomy-aware Sequence Bloom Trees.

Nature biotechnology·2026

Benchmarking Universal Machine-Learning Interatomic Potentials for Accelerated Adsorption Energy Evaluation with DFT Single-Point Calculations.

The journal of physical chemistry letters·2026

CCL19 and CCL21 Display Reciprocal Dependence on R209 in ECL2 of CCR7 for Receptor Activation, Relating to Differences in the Chemokine N-Terminal Region.

Basic & clinical pharmacology & toxicology·2026

Bridging the Computational-Experimental Domain Gap: An Autoencoder-Based Machine Learning Workflow for Raman Spectra Characterization of Amino Acid Mixtures.

The journal of physical chemistry. A·2026

Interpreting Mass Spectrometry Data From Computational Chemistry: A Practical Guide to Reactivity and the Dissociation Mechanisms of 1,4-Naphthoquinone Derivatives.

Journal of mass spectrometry : JMS·2026

Applications of Integrated Molecular Dynamics and Fragment Molecular Orbital (MD+FMO) Calculations in Drug Discovery and Structural Biology.

Methods in molecular biology (Clifton, N.J.)·2026

Perspectives on Hybridizing Quantum Mechanics and Artificial Intelligence for Drug Design.

Methods in molecular biology (Clifton, N.J.)·2026

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In silico predictions; in vivo veritas

Related Concept Videos

Novel multiparameter correlates of Coxiella burnetii infection and vaccination identified by longitudinal deep immune profiling.

HLA- and genotype-based risk assessment model to identify infantile onset pompe disease patients at high-risk of developing significant anti-drug antibodies (ADA).

Can we prevent immunogenicity of human protein drugs?

Clinical validation of the "in silico" prediction of immunogenicity of a human recombinant therapeutic protein.

Confirmation of immunogenic consensus sequence HIV-1 T-cell epitopes in Bamako, Mali and Providence, Rhode Island.

De-immunization of therapeutic proteins by T-cell epitope modification.

Bonsai reconstructs tree representations for distortion-free visualization and exploration of high-dimensional data.

Enhanced antitumor immunity of mRNA vaccines by bioorthogonal-like delayed activation of exogeneous STING.

A blinded, prospective benchmark of in silico antibody discovery anchored to experimental affinity and developability.

High-throughput synthesis of DNA fragments by molecular self-assembly of overlapping oligonucleotides.

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells.

Characterization of microbial dark matter at scale with MetaSBT and taxonomy-aware Sequence Bloom Trees.

Benchmarking Universal Machine-Learning Interatomic Potentials for Accelerated Adsorption Energy Evaluation with DFT Single-Point Calculations.

CCL19 and CCL21 Display Reciprocal Dependence on R209 in ECL2 of CCR7 for Receptor Activation, Relating to Differences in the Chemokine N-Terminal Region.

Bridging the Computational-Experimental Domain Gap: An Autoencoder-Based Machine Learning Workflow for Raman Spectra Characterization of Amino Acid Mixtures.

Interpreting Mass Spectrometry Data From Computational Chemistry: A Practical Guide to Reactivity and the Dissociation Mechanisms of 1,4-Naphthoquinone Derivatives.

Applications of Integrated Molecular Dynamics and Fragment Molecular Orbital (MD+FMO) Calculations in Drug Discovery and Structural Biology.

Perspectives on Hybridizing Quantum Mechanics and Artificial Intelligence for Drug Design.

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In silico predictions; in vivo veritas

Related Concept Videos

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