Drug-induced hemolytic anemias: increasing complications to therapeutic interventions
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Updated: Oct 20, 2026

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Published on: March 14, 2017
1University of Louisville Clinical Laboratory Science Program, KY 40292, USA. michellew@netscape.net
Abstract:
There are recent reports of severe drug-induced immune hemolysis caused by several different classes of drugs. Second and third generation cephalosporins, diclofenac, fludarabine, carboplatin, and beta-lactamase inhibitors are among the drugs associated with severe or fatal hemolysis. Studies on patients who exhibit hemolysis after ingesting these drugs indicate that the four classical mechanisms of drug-induced hemolytic anemia may overlap. These studies appear to support the unified theory for induction of drug-induced immune hemolytic anemia.
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