[Solitary hepatic mass as initial manifestation of non-hodgkin lymphoma]

A 55 years-old woman was admitted to the hospital because fifteen days of malaise, right upper quadrant pain and fever. Physical exam revealed hepato-splenomaly and radiologic evaluation (abdominal ultrasonography and CT) showed a solid hepatic mass with several retroperitoneal lymphadenopathies. Through an hepatic fine needle aspiration biopsy and a bone marrow biopsy, the diagnosis of a high grade non-Hodgkin lymphoma was made. The histopathological study of a retroperitoneal lymphadenopathy surgical biopsy got the definitive diagnosis. This form of liver involvement (big solid hepatic mass) by lymphoma is not usual and when it is found, it's necessary to make a differential diagnosis with primary hepatic tumors, hepatic metastases and primary lymphoma of the liver.