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LipidUNet-Machine Learning-Based Method of Characterization and Quantification of Lipid Deposits Using iPSC-Derived Retinal Pigment Epithelium
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Marked alteration of sterol metabolism and composition without compromising retinal development or function

S J Fliesler1, M J Richards, C Miller

  • 1Department of Ophthalmology, Saint Louis University Eye Institute, Missouri 63104-1540, USA.

Investigative Ophthalmology & Visual Science
|July 7, 1999
PubMed
Summary

Altering retinal sterol metabolism with AY9944 surprisingly did not impair vision in rats, suggesting 7-dehydrosterols may functionally replace cholesterol in the retina.

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