[The safety problems of new vaccines]

The paper characterizes the etiological factors that produce side effects and postvaccinal complications. It presents a classification of the types of sides effects. The study of the immunological safety of vaccines is a new trend in assessing the quality of vaccines and their standardization. Due to the design of new-generation vaccines (gene-engineering, synthetic, DNA vaccines, etc.), their safety gain in their particular significance. It is necessary to make a strict government surveillance over the design, testing of these agents. Possible ways of reducing the adverse effects of vaccines.