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A null HLA-A*68 allele in a bone marrow donor
M Laforet1, N Froelich, A Parissiadis
1Laboratoire d'Histocompatibilité, Etablissement de Transfusion Sanguine, Strasbourg, France. hla@etss.u-strasbg.fr
Tissue Antigens
|July 8, 1999
Abstract:
The authors describe an A*68 allele present at the molecular level but not expressed at the cell surface. This non expression results from the deletion of one nucleotide in exon 1, which causes a shift of the reading frame leading to an early non-sense codon in the same exon.