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Regional drug information service.

U I Schwarz1, S Stoelben, U Ebert

  • 1Institute of Clinical Pharmacology, Faculty of Medicine, University of Technology, Dresden, Germany.

International Journal of Clinical Pharmacology and Therapeutics
|July 8, 1999
PubMed
Summary

This study analyzed inquiries at a German drug information center (DIC). Most questions concerned drug use, adverse reactions, and pregnancy, primarily involving cardiovascular and anti-infective medications, with internists and general practitioners being the main users.

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Area of Science:

  • Pharmacovigilance and Drug Safety
  • Clinical Pharmacy Services
  • Health Services Research

Background:

  • Drug Information Centers (DICs) have been established in Europe for over two decades, with many German centers founded in the 1990s.
  • A specific regional, university hospital-based DIC has been operational for three and a half years, serving physicians.

Purpose of the Study:

  • To characterize the types of inquiries received by a regional drug information service.
  • To identify the user profile of physicians utilizing the drug information service.

Main Methods:

  • Analysis of 516 inquiries received by a regional drug information center in Dresden, Germany.
  • Classification of inquiry topics (e.g., adverse reactions, pharmacokinetics) and drug types (using Anatomical Therapeutic Chemical classification).

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  • Categorization of users by medical specialty.

    • Main Results:

    • The most frequent inquiry topics included therapeutic use (34%), adverse drug reactions (28%), pregnancy/lactation (16%), and pharmacokinetics/dosage (15%).
    • Predominant drug categories involved were cardiovascular (20%), systemic anti-infectives (19%), central nervous system agents (15%), and alimentation/metabolism drugs (9%).
    • Primary users were internists (19%), general practitioners (19%), pediatricians (18%), and gynecologists (11%).

    Conclusions:

    • The inquiry types and user demographics align with those reported by other European DICs.
    • The service is actively disseminating information through educational bulletins on clinically relevant drug topics.