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Cytotoxic 3,4-secoapotirucallanes from Aaglaia argentea bark
K Mohamad1, M T Martin, H Najdar
1Institut de Chimie des Substances Naturelles, C.N.R.S., 91198 Gif-sur-Yvette Cedex, France.
Journal of Natural Products
|July 8, 1999
Abstract:
Nine 3,4-secoapotirucallanes, argentinic acids A-I, were isolated from the bark of Aglaia argentea and transformed to their methyl esters 1-9. The structures were determined by spectral and chemical means. Compounds 1-8 showed moderate cytotoxic activity against KB cells (IC50 1.0-3.5 microg/mL).