Related Experiment Video
Updated: Aug 18, 2026

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products
Published on: March 12, 2020
Madangolide and laingolide A, two novel macrolides from lyngbya bouillonii (Cyanobacteria)
1Laboratory of Bio-organic Chemistry, Faculty of Sciences CP 160/07, University of Brussels, 50, Av. F. D. Roosevelt, B-1050 Brussels, Belgium, and Laboratory of Algology, Mycology and Experimental Systematics, Department of Botany, University.
Abstract:
Two new macrolide derivatives, madangolide (2) and laingolide A (3), have been isolated from the cyanobacterium Lyngbya bouillonii, collected in Papua New Guinea. Their structures (without stereochemistry) have been established by detailed high-field 1D and 2D NMR studies and, in the case of 3, by comparison with the spectroscopic data of laingolide (1), previously isolated from the same organism.

