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Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
Published on: September 19, 2018
[Coronary disease in patients with an abdominal aortic aneurysm]
M Garofalo1, R Borioni, P Nardi
1Cattedra di Cardiochirurgia, Università di Roma Tor Vergata, European Hospital.
Insights
Coronary artery disease (CAD) is common in patients undergoing abdominal aortic aneurysm (AAA) repair. Invasive coronary assessment and treatment before AAA surgery are recommended to improve outcomes and prevent cardiac complications.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Vascular Surgery
Context:
- Abdominal aortic aneurysm (AAA) repair is a major vascular procedure.
- Coronary artery disease (CAD) significantly impacts outcomes after AAA repair.
- Pre-operative cardiac evaluation is crucial for patient management.
Purpose:
- To evaluate the diagnostic yield and therapeutic implications of coronary angiography in patients with AAA.
- To assess the incidence of significant CAD in AAA patients.
- To determine the safety and efficacy of concurrent CAD treatment and AAA repair.
Summary:
- A study of 126 AAA patients undergoing elective repair found a high incidence (35.7%) of significant CAD requiring intervention.
- Coronary angiography was performed in symptomatic patients, those with prior myocardial infarction, or previous coronary artery bypass.
- 37 patients underwent coronary artery bypass grafting (CABG) and 8 had percutaneous coronary angioplasty (PTCA) prior to AAA repair, with no reported cardiac or vascular morbidity/mortality.
Impact:
- Invasive coronary assessment is strongly suggested for AAA patients with cardiac symptoms or history.
- Early diagnosis and treatment of CAD can reduce perioperative cardiac complications and improve long-term survival after AAA repair.
- This approach supports a strategy of comprehensive pre-operative cardiac management in high-risk vascular patients.
Abstract:
The presence of coronary artery disease (CAD) evaluated with coronary angiography and eventual correction of CAD in abdominal aortic aneurysm (AAA) patients has been considered the main determinant of early and late outcome after AAA repair. This study reports our experience in CAD and AAA patients in terms of diagnosis and therapy of CAD. In a population of 126 patients (122 males, 4 females, mean age 67.5 years, range 37-81) who were candidates to elective repair for AAA with a diameter > or = 5 centimeters, we included coronary arteriography in 1) patients who were symptomatic for angina (15.9%); 2) patients with previous myocardial infarction (33.3%); 3) patients with previous coronary artery bypass (4%). We identified a group of 45 patients (35.7%) with significant CAD who had been treated before AAA surgery by coronary artery bypass grafting (CABG) in 37 cases or percutaneous coronary angioplasty (PTCA) in 8 cases. AAA repair was performed during the same hospital stay or at a later date. We did not report any morbidity and mortality related to cardiac or vascular procedures. We believe that among patients reporting cardiac symptoms (previous myocardial infarction, angina) the incidence of surgically-correctable CAD is not negligible (45/67, 67.2%). Therefore, invasive coronary study is strongly suggested in such cases to reveal and treat an eventual coronary artery stenosis prior to AAA repair. The absence of cardiac morbidity and mortality related to cardiac and vascular procedures supports this approach.
Related Concept Videos
Aortic Regurgitation III: Medical Management
Coronary Artery Disease I: Introduction
Coronary Artery Disease III: Clinical Manifestations
Aneurysm I: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm III: Interprofessional Care

