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Landomycin A inhibits DNA synthesis and G1/S cell cycle progression
R T Crow1, B Rosenbaum, R Smith
1Department of Chemistry, Texas A&M University, College Station 77842, USA.
Bioorganic & Medicinal Chemistry Letters
|July 9, 1999
Abstract:
Landomycin A was found to inhibit the uptake of [3H]thymidine into DNA in murine smooth muscle cells indicating decreased DNA synthesis. Subsequent studies showed that landomycin A inhibits cell cycle progression.
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