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Eosinophilic granuloma: a case report with pathologic fracture
A M Holzhauer1, R A Abdelsayed, S H Sutley
1Oral Biology and Maxillofacial Pathology Department, School of Dentistry, Medical College of Georgia, Augusta 30912-1001, USA.
Summary
Eosinophilic granuloma of the jaw, a rare condition, often presents as a mass. This case highlights an unusual initial symptom: mandibular body fracture in a woman.
Area of Science:
- Oral pathology
- Maxillofacial surgery
- Oncology
Background:
- Eosinophilic granuloma (EG) is a rare disorder characterized by the proliferation of histiocytes and eosinophils.
- Approximately 10%–20% of EG cases involve the jaws, typically presenting as a palpable mass.
- Common oral signs include gingivitis, tooth mobility, and non-healing ulcers.
Observation:
- A 38-year-old woman presented with a mandibular body fracture.
- This fracture was the initial manifestation of monostotic (single bone) eosinophilic granuloma.
- This presentation is unusual and infrequently documented for jaw EG.
Findings:
- The case details the clinical and radiographic features of mandibular eosinophilic granuloma presenting as a fracture.
- Differential diagnosis considerations for jaw lesions are discussed.
- The management and treatment plan for this specific case are outlined.
Implications:
- Highlights the importance of considering eosinophilic granuloma in the differential diagnosis of jaw fractures.
- Underscores the variability in clinical presentation of eosinophilic granuloma.
- Contributes to the literature on rare manifestations of eosinophilic granuloma in the maxillofacial region.