Microporous segmented polyetherurethane vascular graft: I. Dependency of graft morphology and mechanical properties...

The influence of polyurethane compositions and fabrication conditions on the pore morphology and mechanical properties of microporous segmented polyetherurethane (SPEU) grafts, which were produced by the coagulation technique, were carefully investigated in this article. SPEU resins based on polytetramethylene oxide (PTMO) were synthesized by the solution polymerization method. Different types of coagulant were adapted to examine the feasibility of producing a microporous SPEU graft with good structural regularity. The experimental results indicate that a microporous SPEU graft with a uniform pore structure can be fabricated quite conveniently by using a proper concentration of water and ethanol mixed coagulant. Tensile tests demonstrated that the fabricated microporous SPEU grafts possess high mechanical strengths and satisfy the requirements as vessel replacements. The burst strength test also revealed that the SPEU graft can sustain extremely high internal pressure. Furthermore, a high compliant SPEU (high porosity) graft can be obtained by blending a proper amount of "soluble filler" (i.e., free PTMO polyol in this study) into the SPEU resin.