[Detection of Epstein-Barr virus in Malt type gastric malignant lymphoma using in situ hybridization]

¹Service d'Anatomie Pathologique, Hôpital Militaire, Tunis, Tunisie.

Clinical and Experimental Pathology

|July 10, 1999

Abstract:

The aim of our study was to look for Epstein Barr virus (EBV) genome by in situ hybridization in 23 MALT gastric lymphomas. 15 cases were of low grade, and 8 were of high grade malignancy. We obtained a positive result in 3 cases (13%) of low grade lymphomas. EBV was present in few centrocyte-like and centroblastic cells. Literature review shows an EBV infection rate varying between 8 and 12% with variables results which don't allow strong and reliable conclusion. An etiopathogenic role for EBV in Malt gastric lymphoma remain yet hypothetic.

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Abstract:

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