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CT-guided 14-G cutting needle lung biopsy in children: safe and effective
A G Wilkinson1, J Y Paton, N Gibson
1Radiology Department, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK.
Insights
CT-guided percutaneous lung biopsy in children with chronic respiratory disease yielded adequate tissue for diagnosis. This minimally invasive method proved safe and effective, with minor complications that did not require intervention.
Area of Science:
- Pediatric Pulmonology
- Interventional Radiology
- Diagnostic Pathology
Background:
- Chronic respiratory diseases in children often necessitate tissue diagnosis.
- Open lung biopsy carries significant risks for pediatric patients.
- Minimally invasive biopsy techniques are sought for improved safety and outcomes.
Purpose of the Study:
- To evaluate the efficacy and safety of CT-guided percutaneous lung biopsy in children.
- To assess the adequacy of tissue samples obtained for histological examination.
- To compare this technique with traditional open-lung biopsy.
Main Methods:
- Seven CT-guided percutaneous lung biopsies were performed using a 14-G automatic cutting needle.
- Procedures were conducted in six pediatric patients with chronic respiratory disease.
- Local anesthesia was predominantly used, with one to two tissue cores obtained per procedure.
Main Results:
- Adequate tissue for histological examination was obtained in all seven procedures.
- Minor pneumothorax and/or haemothorax occurred in most cases, visible only on CT and managed conservatively.
- No major complications were observed, indicating a favorable safety profile.
Conclusions:
- CT-guided percutaneous 14-G automatic cutting-needle biopsy is a safe and effective minimally invasive alternative for pediatric lung tissue sampling.
- This technique provides adequate diagnostic tissue with a low complication rate in children with chronic respiratory disease.
Abstract:
CT-guided percutaneous lung biopsy was performed in children with chronic respiratory disease to obtain samples for histological examination. An automatic cutting device with a 14-G needle was used with one or two cores obtained in each procedure. Seven procedures were performed in six children, mostly with local anaesthesia. Adequate tissue was obtained in all cases. Although a small pneumothorax and/or haemothorax occurred in most procedures, these were usually visible only on CT and did not require active management. A larger pneumothorax in one child also resolved with conservative management. Percutaneous CT-guided 14-G automatic cutting-needle biopsy of lung parenchyma in children is a minimally invasive alternative to open-lung biopsy with no complications in our series.