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Updated: Aug 6, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
Published on: July 3, 2015
[Chromosome aberrations as a bio-dosimetric test of space radiation (experimental data from the seeds of higher
Abstract:
The authors analyzed the data about seeds of higher plants obtained in space experiments from several days to a year and a half in duration, and ground-based simulation studies on beams of accelerated heavy ions by the universal biological criterion of the chromosome aberrations. The criterion was also used to compare these data with those about lymphocytes in human peripheric blood in vitro. The number of aberrant cells, including cells with multiple aberrations, grew with mission duration, absorbed dose, and fluence of heavy charged particles as well as the topography of particles traverse of cells. Methodical dimensions of the test-object as a detector to evaluate the biological effects of and risk from space radiation in long-term space missions are considered.
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