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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment

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Extrahepatic drug metabolizing enzymes.

J Kapitulnik1, H W Strobel

  • 1Department of Pharmacology, School of Pharmacy, Faculty of Medicine, Hebrew University of Jerusalem, Israel.

Journal of Biochemical and Molecular Toxicology
|July 14, 1999
PubMed
Summary

Extrahepatic drug-metabolizing enzymes show unique regulation tied to tissue function. Hormonal effects on these enzymes may involve tissue-specific transcription factor activity.

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