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Prevalence of rotavirus diarrhoea among hospitalized children in Pune, India

S D Kelkar1, S G Purohit, K V Simha

  • 1National Institute of Virology, Pune.

The Indian Journal of Medical Research
|July 14, 1999
PubMed

Insights

Rotavirus diarrhea is common in children under five, with most cases occurring in winter. Infants aged 6-24 months and males are most susceptible to this viral infection.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Rotavirus is a leading cause of severe diarrheal disease in infants and young children globally.
  • Understanding the epidemiological patterns of rotavirus infection is crucial for public health interventions.

Purpose of the Study:

  • To investigate the prevalence and epidemiological characteristics of rotavirus infections in children under five years of age.
  • To identify risk factors associated with rotavirus diarrhea, including age, sex, and seasonality.

Main Methods:

  • A retrospective analysis of 945 fecal specimens collected from children aged 5 years or younger between July 1992 and June 1996.
  • Statistical analysis including odds ratios and multivariate logistic regression to assess the influence of various factors on rotavirus prevalence.

Main Results:

  • Rotavirus was detected in 28.15% (266/945) of the collected fecal specimens.
  • Rotavirus diarrhea cases showed a strong seasonal pattern, with peak incidence in winter and lowest incidence during the rainy season.
  • The age group of 6-24 months was found to be the most susceptible, and the disease was more prevalent in males.

Conclusions:

  • Rotavirus infection is a significant cause of diarrhea in young children, with distinct seasonal and age-related patterns.
  • Male gender and winter season are identified as risk factors for rotavirus diarrhea in this population.
  • These findings highlight the importance of considering age and seasonality in the prevention and management of rotavirus infections.

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