[Anesthesia in a patient with epidermolysis bullosa]

Epidermolysis bullosa hereditaria, a rare inherited disorder presents clinically with recurrent cutaneous blister formation with possible involvement of mucous membrane and organs following minimal trauma. The sequelae of this disease pose significant anesthetic problems to operating room staffs. We describe the anesthetic management of a 32-year old woman with epidermolysis bullosa hereditaria who underwent palmar skin graft using regional anesthesia, and discuss the problems associated with this disease.