Related Experiment Videos
Safety of viral DNA in biological products
1Office of Vaccines Research and Review, Food and Drug Administration, Bethesda, MD, USA.
Abstract:
Data from studies of the infectivity of DNA injected directly into laboratory animals are used to estimate the potential infectivity risk of residual DNA in biological products. The potential for some novel products to contain infectious quantities of residual cellular DNA is discussed, and further study of this subject is suggested.