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Multiple myeloma evaluated with 201Tl scintigraphy compared with bone scintigraphy
N Watanabe1, M Shimizu, M Kageyama
1Department of Radiology, Toyama Medical and Pharmaceutical University, Toyama City, Japan.
Unlabelled:
The purpose of this study was to investigate the clinical usefulness of 201Tl chloride scintigraphy in the diagnostic evaluation of 20 patients with multiple myeloma (19/20 patients) or extramedullary plasmacytoma (1/20 patients) in comparison with bone scintigraphy.
Methods:
Both 201Tl and bone scintigraphy were performed to obtain planar images on the same instrument.
Results:
201Tl scintigraphy showed increased uptake in 15 of 20 patients (75%) and was negative in 5 of 20 patients (25%). In addition, 201Tl scintigraphy of multiple myeloma was more useful in detecting the lesions in 11 of 17 patients and less useful in 6 of 17 patients than bone scintigraphy.
Conclusion:
The combination of 201Tl and bone scintigraphy, compared with bone scintigraphy alone, shows promise in more accurately diagnosing multiple myeloma.