Method for liquid-liquid extraction of blood surrogates for assessing human exposure to jet fuel

A baseline method of liquid-liquid extraction for assessing human exposure to JP-8 jet fuel was established by extracting several representative compounds ranging from very volatile to semi-volatile organic compounds, including benzene, toluene, nonane, decane, undecane, tridecane, tetradecane and pentadecane, from PBS buffer. Some specific techniques for solvent selection, solvent evaporation, and GC analysis were developed to accommodate this wide range of constituents of JP-8. The application of the established method to the extraction and quantitative analysis of JP-8 from PBS and bovine plasma was demonstrated.