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On the analogy between forskolin and D-glucose
1Laboratoire d'Etudes Dynamiques et Structurales de la Sélectivité UMR CNRS 5616, Université de Grenoble, France.
Bioorganic & Medicinal Chemistry Letters
|July 16, 1999
Abstract:
2-O-Acetyl-D-glucose was synthesized in order to evaluate the influence of an acyl group on the binding with the glucose carrier protein (GluT); as its affinity neighbours that of glucose itself, the glucose-forskolin analogy appears to be coincidental and several explanations are proposed.