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[Detection of antibacterial activity in the urine of children: a comparison of three tests]

J E Hoppe1, M Schlegel

  • 1Universitäts-Kinderklinik, Tübingen.

Klinische Padiatrie
|July 17, 1999
PubMed

Insights

The Bacillus subtilis agar diffusion test is the most accurate method for detecting antibacterial activity in children's urine. This reliable method aids in diagnosing urinary tract infections and monitoring antibiotic treatment effectiveness.

Area of Science:

  • Clinical Microbiology
  • Pediatric Infectious Diseases

Background:

  • Detecting antibacterial activity in urine is crucial for diagnosing urinary tract infections (UTIs).
  • It also helps assess patient adherence to antibiotic regimens.

Purpose of the Study:

  • To evaluate the reliability of the Bacillus subtilis agar diffusion test compared to commercial test strips for detecting antibacterial activity in pediatric urine samples.

Main Methods:

  • Examined 566 urine samples from 431 pediatric inpatients.
  • Utilized the Bacillus subtilis agar diffusion test, Micur BT, and Urotest AB.

Main Results:

  • The Bacillus subtilis agar diffusion test demonstrated the highest accuracy at 98.8%.
  • Micur BT exhibited lower specificity (87.6%), while Urotest AB showed lower sensitivity (86.0%).

Conclusions:

  • The Bacillus subtilis agar diffusion test is the most reliable method for detecting antibacterial activity in pediatric urine.
  • This finding supports its use in clinical settings for children.
Abstract

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