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Trigeminal neuropathy secondary to perineural invasion of head and neck carcinomas
R H Boerman1, E M Maassen, J Joosten
1Department of Neurology, University Hospital Nijmegen, The Netherlands.
Neurology
|July 17, 1999
Abstract:
Perineural spread of head and neck cancer is an uncommon cause of cranial neuropathy. We studied five patients with cranial neuropathy resulting from perineural spread of head and neck carcinomas. Trigeminal neuropathy with facial pain or paresthesias was the most common clinical manifestation. MRI in the coronal plane under gadolinium enhancement established the diagnosis by visualization of the lower divisions of the trigeminal nerve. Perineural tumor spread can cause headaches in patients with head and neck cancer.