Multiple cerebral infarctions associated with ovarian hyperstimulation syndrome
F Yoshii1, N Ooki, Y Shinohara
1Department of Neurology, Tokai University School of Medicine, Isehara, Japan. yoshii@is.icc.u-tokai.ac.jp
Neurology
|July 17, 1999
Abstract:
A 26-year-old woman on human menopausal gonadotrophin-human chorionic gonadotrophin therapy for sterility showed multiple cerebral infarctions associated with ovarian hyperstimulation syndrome. A hypercoagulable state (hemoconcentration, increased plasma levels of D-dimer and thrombin-antithrombin III complex, and decreased protein S activity) was associated with her thromboembolic events. Cerebral infarction associated with mild neurologic deficits may be overlooked in patients with ovarian hyperstimulation syndrome.
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