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Updated: Aug 11, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Applications for guided bone regeneration in endodontic surgery
N Mastromihalis1, S Goldstein, M Greenberg
1State University at Stony Brook School of Dental Medicine, Department of Endodontics, USA.
Abstract:
Regeneration of apical bony defects remains a significant problem in endodontic surgery. When a resorbable membrane is placed over a defect, it acts as a barrier between the defect and the overlying gingival tissue. This barrier membrane provides sufficient time for bone to regenerate while preventing the faster growing connective tissue from invaginating into the area. When new tissue replicates the structure and function of the lost tissue, then apical regeneration has occurred.

