Related Experiment Video

Updated: Jul 28, 2026

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion
08:34

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion

Published on: February 24, 2021

[Reasons for fresh frozen plasma transfusion in a general hospital]

L Pita-Ramírez1, B E Cabrera Carbajal, C Ortega Zavala

  • 1Servicio de Hematología, Hospital General Vasco de Quiroga (HG-VQ), Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Morelia, Michoacán. pital@mail.giga.com

Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion
|July 20, 1999
PubMed
Abstract

Insights

Fresh-frozen plasma (FFP) transfusions in a Mexican hospital were rarely indicated appropriately. Over 96% of FFP units were transfused without meeting current transfusion guidelines, highlighting a significant need for improved clinical practice.

Area of Science:

  • Transfusion Medicine
  • Hematology
  • Clinical Pathology

Background:

  • Fresh-frozen plasma (FFP) is a blood product used to correct coagulation factor deficiencies.
  • Appropriate transfusion guidelines exist to ensure effective and safe use of FFP.
  • Assessing transfusion practices is crucial for optimizing patient care and resource allocation.

Purpose of the Study:

  • To evaluate the indications for fresh-frozen plasma (FFP) transfusions in a Mexican hospital.
  • To determine the adherence to established FFP transfusion guidelines.

Main Methods:

  • A retrospective analysis of FFP transfusions was conducted.
  • The study period was February to August 1998.
  • Transfusions were classified as appropriate or inappropriate based on recent FFP transfusion guidelines.

Main Results:

  • A total of 292 FFP units were transfused in 78 patients.
  • Only 3.76% of FFP units (11 units) were transfused appropriately.
  • A significant majority, 96.23% (281 units), were inadequately indicated, with many for unspecified reasons or suboptimal coagulation index values.

Conclusions:

  • The study found a very low rate of appropriate fresh-frozen plasma (FFP) transfusions in the evaluated Mexican hospital.
  • Current FFP transfusion practices deviate significantly from established guidelines.
  • There is a critical need for education and implementation of evidence-based transfusion protocols to improve FFP utilization.

More Related Videos

Platelet-Rich Plasma Lysate for Treatment of Eye Surface Diseases05:57

Platelet-Rich Plasma Lysate for Treatment of Eye Surface Diseases

Published on: August 2, 2022

Determination of the Procoagulant Activity of Extracellular Vesicle (EV) Using EV-Activated Clotting Time (EV-ACT)04:56

Determination of the Procoagulant Activity of Extracellular Vesicle (EV) Using EV-Activated Clotting Time (EV-ACT)

Published on: August 4, 2023

Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...