[Hematologic tumors]

Hematologic tumors are commonly systemic on diagnosis, and chemotherapy is therefore the sole method by which to obtain a prolongation of survival or cure. Based upon results from a prospective randomized trial compared to a combination regimen consisting of daunorubicin and cytarabine, the first line chemotherapeutic regimen for acute myelogenous leukemia is considered to be a combination regimen consisting of idarubicin and cytarabine. The standard chemotherapeutic regimen for advanced Hodgkin's disease would seem to be an ABVD regimen, judging from results reported from a prospective randomized trial which compared MOPP, ABVD and MOPP-ABVD. The first generation combination CHOP is recognized as a standard regimen for advanced non-Hodgkin lymphoma due to results of a prospective randomized trial compared with intensive chemotherapeutic regimens.