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An open study of tinea capitis in 50 children treated with a 2-week course of oral terbinafine

B Krafchik1, J Pelletier

  • 1Division of Dermatology, The Hospital for Sick Children, University of Toronto, Ontario, Canada.

Journal of the American Academy of Dermatology
|July 20, 1999
PubMed

Insights

Terbinafine effectively treats pediatric tinea capitis, especially infections caused by Trichophyton species. This study found it safe and well-tolerated in children.

Area of Science:

  • Dermatology
  • Mycology
  • Pediatrics

Background:

  • Terbinafine is a standard antifungal medication for dermatophyte infections.
  • Previous research indicates terbinafine's efficacy in treating tinea capitis, particularly Trichophyton species.

Purpose of the Study:

  • To evaluate the safety and effectiveness of terbinafine in treating pediatric tinea capitis.

Main Methods:

  • An open-label study involving 50 children diagnosed with tinea capitis.
  • Treatment with oral terbinafine for a duration of two weeks.

Main Results:

  • Over 86% of patients achieved clinical and mycological cure.
  • No adverse side effects were reported, and patient compliance was high.

Conclusions:

  • Terbinafine demonstrates significant safety and effectiveness for treating tinea capitis in children.
  • The drug is particularly effective against tinea capitis caused by Trichophyton species.
Abstract

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