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The course of the remnant kidney model in mice
1Department of Medicine, School of Medicine, University of Minnesota, Minneapolis 55455, USA.
Kidney International
|July 20, 1999
Abstract:
The remnant kidney model was produced in mice by unilateral nephrectomy and partial infarction of the remaining kidney. Control mice underwent laparotomy only. The mice were studied for up to 44 weeks. No quantitative differences were noted in systolic arterial pressure, proteinuria, or histopathology between control mice and those with a remnant kidney. Glomerular enlargement occurred in the remnant kidney.
