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Related Experiment Videos

Reference values for lung function tests. II. Maximal respiratory pressures and voluntary ventilation.

J A Neder1, S Andreoni, M C Lerario

  • 1Department of Physiology, St. George's Hospital Medical School, University of London, UK.

Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
|July 21, 1999
PubMed
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This study establishes new reference values for respiratory muscle strength in healthy Brazilian adults. These findings provide crucial data for evaluating lung function and muscle strength in clinical and research settings.

Area of Science:

  • Pulmonary Medicine
  • Physiology
  • Exercise Science

Background:

  • Respiratory muscle strength is vital for health and can be measured using static (MIP, MEP) and dynamic (MVV) tests.
  • Existing reference values for these tests are limited, particularly for diverse populations like Brazilians.
  • There is a need for population-specific data to accurately assess respiratory muscle function.

Purpose of the Study:

  • To establish gender-specific reference values for maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), and maximal voluntary ventilation (MVV) in a healthy adult Brazilian population.
  • To develop prediction equations for MIP, MEP, and MVV based on age and anthropometric measurements.
  • To compare the obtained reference values with those from previous international studies.

Main Methods:

Related Experiment Videos

  • Prospective evaluation of 100 healthy, non-smoking Brazilian adults (50 males, 50 females) aged 20-80 years.
  • Development of gender-specific linear prediction equations for MIP, MEP, and MVV using multiple regression analysis.
  • Correlation analysis between respiratory muscle strength, anthropometric data, physical activity levels, and aerobic power.

Main Results:

  • Age and anthropometric measurements explained up to 56% of the variability in respiratory muscle strength.
  • Previous international reference values systematically underestimated observed MIP values in the Brazilian sample.
  • Regular physical activity and aerobic power showed strong correlations with respiratory and peripheral muscle strength.

Conclusions:

  • The study provides novel, gender-specific reference equations for evaluating respiratory muscle strength in Brazilians aged 20-80.
  • These findings offer a more accurate frame of reference for clinical and research assessments compared to existing international data.
  • Physical activity level is a significant factor influencing respiratory and overall muscular strength.