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Identification of additional members define a Plasmodium falciparum gene superfamily which includes Pfs48/45 and

T J Templeton1, D C Kaslow

  • 1Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0425, USA. ttempleton@atlas.niaid.nih.gov

Molecular and Biochemical Parasitology
|July 21, 1999
PubMed
Abstract

No abstract available in PubMed .

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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
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