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Related Experiment Videos

Bone scintigraphy in tuberculous spondylodiscitis.

H G Pandit1, P D Sonsale, S S Shikare

  • 1Queen Alexandra Hospital, Cosham, Portsmouth, UK.

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
|July 21, 1999
PubMed
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Bone scintigraphy is a highly sensitive tool for diagnosing spinal tuberculosis (tuberculous spondylodiscitis), detecting abnormalities in 95% of patients. This imaging technique aids in management before treatment begins.

Area of Science:

  • Nuclear Medicine
  • Orthopedic Surgery
  • Infectious Diseases

Background:

  • Spinal tuberculosis (tuberculous spondylodiscitis) can present subtly, often missed by plain radiography.
  • Early and accurate diagnosis is crucial for effective management of spinal tuberculosis.

Purpose of the Study:

  • To evaluate the diagnostic utility and sensitivity of bone scintigraphy using 99mTc-MDP in patients with suspected tuberculous spondylodiscitis.
  • To assess the patterns of radionuclide uptake and identify associated lesions in spinal tuberculosis.

Main Methods:

  • Retrospective analysis of 40 patients who underwent bone scan with 99mTc-MDP prior to anti-tuberculous therapy or surgery.
  • Evaluation of scintigraphic findings, including uptake patterns, multicentricity, and extra-spinal lesions (skull, ribs).

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Main Results:

  • Bone scintigraphy demonstrated high sensitivity (95%), with abnormal uptake in 38 out of 40 patients.
  • Multicentric tuberculous lesions were identified in 25% of cases.
  • Rib lesions were observed in six patients, characterized by a typical band-like uptake pattern.

Conclusions:

  • Bone scintigraphy is a valuable and sensitive diagnostic tool for tuberculous spondylodiscitis, surpassing plain radiography in detecting spinal and associated lesions.
  • The study highlights the advantages and limitations of bone scanning in the comprehensive management of spinal tuberculosis.