Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Appendicitis is a place for clinical judgement.

E Bergeron1, B Richer, R Gharib

  • 1Department of General Surgery, Centre Hospitalier Laurentien, Ste-Agathe des Monts, Quebec, Canada.

American Journal of Surgery
|July 22, 1999
PubMed
Summary

This study examined how well doctors can diagnose appendicitis using only clinical information before surgery. Researchers reviewed records of 237 patients with suspected appendicitis and found that delays in seeking medical care were strongly linked to complicated disease. About 32% of cases were complicated, and 8.4% had negative exploration. The study suggests that clinical judgment can reliably predict disease severity, with consultation delay being the strongest indicator. No other factors reached statistical significance. These findings support the use of clinical data in diagnostic decision-making for appendicitis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Community Health Navigators for Cancer Screening Among Deaf, Deafblind, and Hard of Hearing Adults Who Use American Sign Language.

Journal of cancer education : the official journal of the American Association for Cancer EducationĀ·2024
Same author

Vaccination with the Crimean-Congo hemorrhagic fever virus viral replicon vaccine induces NP-based T-cell activation and antibodies possessing Fc-mediated effector functions.

Frontiers in cellular and infection microbiologyĀ·2023
Same author

Actinomycetoma caused by <i>Gordonia westfalica</i>: first reported case of human infection.

New microbes and new infectionsĀ·2020
Same author

Assessment of VITEKĀ® MS IVD database V3.0 for identification of Nocardia spp. using two culture media and comparing direct smear and protein extraction procedures.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical MicrobiologyĀ·2019
Same author

Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide.

CellR4-- repair, replacement, regeneration, & reprogrammingĀ·2019
Same author

Antibiotic susceptibility testing and species identification of Nocardia isolates: a retrospective analysis of data from a French expert laboratory, 2010-2015.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious DiseasesĀ·2018

Area of Science:

  • Acute abdominal conditions in general surgery
  • Clinical decision-making in emergency medicine
  • Surgical outcomes research in gastroenterology

Background:

Diagnosing acute appendicitis remains challenging despite advances in medical imaging and clinical guidelines. Existing literature highlights variability in diagnostic accuracy, with negative appendectomies reported in 9% to 40% of cases. Prior research has shown that clinical assessment alone can lead to diagnostic uncertainty. No prior work had resolved the specific factors contributing to complicated appendicitis. That uncertainty drove this study's focus on clinical performance and associated variables. It was already known that delays in seeking care influence outcomes in acute conditions. However, the relationship between consultation delay and appendicitis severity had not been clearly established. This gap motivated an analysis of preoperative clinical indicators and their association with disease complexity. The study aimed to clarify how clinical judgment alone might predict complicated appendicitis.

Purpose Of The Study:

Keywords:
acute appendicitis diagnosisclinical decision-makingsurgical outcomesemergency medicine

Frequently Asked Questions

The authors propose that consultation delay is the strongest predictor of complicated appendicitis.

The study analyzed 237 cases of appendicitis diagnosed between 1994 and 1997.

Delays before first medical consultation were significantly longer in complicated cases compared to noncomplicated cases.

Eight point four percent of cases had negative exploration according to the study findings.

Multivariate analysis was performed using logistic regression techniques.

Related Experiment Videos

The study aimed to evaluate clinical performance in diagnosing appendicitis and identify factors linked to complicated disease. Researchers focused on the role of clinical judgment in distinguishing noncomplicated from complicated cases. They sought to determine if clinical data alone could reliably predict disease severity. The motivation stemmed from high rates of negative appendectomies and diagnostic uncertainty. The study examined how delays in seeking care might influence outcomes. It also aimed to assess whether clinical indicators could reduce misdiagnosis rates. The goal was to provide evidence for the reliability of clinical judgment in this context. By analyzing patient records, the researchers aimed to clarify the role of consultation timing in disease progression.

Main Methods:

The study reviewed medical records of patients diagnosed with appendicitis between 1994 and 1997. Researchers collected demographic, clinical, and paraclinical data for analysis. A total of 237 cases were included in the study population. Multivariate analysis was performed using logistic regression techniques. The dataset included both preoperative and postoperative diagnoses. Clinical indicators were compared across three diagnostic categories. Researchers assessed the association between consultation delay and disease severity. The analysis focused on identifying statistically significant predictors of complicated appendicitis.

Main Results:

Of the 214 evaluable cases, 59.4% had noncomplicated appendicitis, 32.2% had complicated appendicitis, and 8.4% had negative exploration. Delays before first medical consultation were longest in complicated cases at 3.30 days. Patients with negative exploration also showed a delay of 3.00 days compared to 1.24 days in noncomplicated cases. The difference in consultation delay was statistically significant (P < 0.001). Clinical data alone showed acceptable accuracy in predicting disease severity. No other demographic or clinical factor reached statistical significance. The association between consultation delay and complicated disease remained strong. These findings suggest clinical judgment can reliably identify disease complexity.

Conclusions:

The authors propose that clinical judgment alone can reliably distinguish noncomplicated from complicated appendicitis. They suggest that consultation delay is the strongest predictor of disease severity. The study supports the use of clinical indicators in diagnostic decision-making. No other variable reached statistical significance in predicting complicated disease. The findings suggest that early consultation improves diagnostic accuracy. The authors emphasize the importance of timely medical evaluation. They propose that clinical performance remains a valid approach in appendicitis diagnosis. The study does not claim that imaging is unnecessary but suggests clinical data can be sufficient.

The authors suggest that clinical judgment alone can reliably distinguish noncomplicated from complicated appendicitis.