Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Computational methods for ultrasonic bone assessment.

G Luo¹, J J Kaufman, A Chiabrera

¹New York Department of Veterans Affairs Medical Center and Department of Rehabilitation Medicine, New York University Medical Center, NY, USA.

Ultrasound in Medicine & Biology

|July 22, 1999

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hypertension and myocardial fibrosis: A systematic review and meta-analysis.

Clinical radiology·2026

Same author

[Predictive value of lung ultrasound scores for bronchopulmonary dysplasia in very low birth weight infants with patent ductus arteriosus].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2026

Same author

Safety and feasibility of combined transanal total mesorectal excision with delayed coloanal anastomosis in high-risk patients with low rectal cancer.

Techniques in coloproctology·2026

Same author

Advances in the application of natural bioactive compounds for the prevention and control of porcine epidemic diarrhea virus via the oxidative stress pathway.

Polish journal of veterinary sciences·2026

Same author

[Molecular mechanisms of the TRPV4-RhoA/ROCK1 signaling axis in mediating mechanical stress-induced myocardial fibrosis in fetuses with tetralogy of Fallot].

Zhonghua xin xue guan bing za zhi·2026

Same author

[Analysis of optimizing indications for fetal pulmonary valvuloplasty based on a multi-parameter scoring system].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2026

Same journal

Cardiac Natural Mechanical Wave Detection and Speed Estimation Using Deep Learning-Based 2-D Ultrasound Imaging: A Feasibility Study.

Ultrasound in medicine & biology·2026

Same journal

Region-Specific Evaluation of Plaque Segmentation in Cross-sectional Projections of Carotid Ultrasound Images Using Deep Learning Models in a Sub-clinical Atherosclerosis Cohort.

Ultrasound in medicine & biology·2026

Same journal

Simulating the Dedifferentiation Process of Thyroid Cancer: Insights from Mouse Models and Ultrasound Imaging.

Ultrasound in medicine & biology·2026

Same journal

A Nomogram Based on Ultrasound Features for Predicting Major Intra-Operative Hemorrhage in Patients With Placenta Accreta Spectrum (PAS).

Ultrasound in medicine & biology·2026

Same journal

MedLP-HAFB-CLIP: Hierarchical Adaptive Large Model With Learnable Medical Prompts for Level II Ultrasound Standard Plane Identification.

Ultrasound in medicine & biology·2026

Same journal

Data Assimilating B-splines for Model-based Regularization in Ultrasound Vector Flow Imaging.

Ultrasound in medicine & biology·2026

See all related articles

Ultrasound assessment of bone strength is complex. This study used simulations to show that both bone density and architecture influence ultrasound wave propagation, impacting fracture risk evaluation.

Area of Science:

Biomedical Engineering
Materials Science
Medical Imaging

Background:

Ultrasound shows promise for noninvasively assessing bone strength and fracture risk.
Understanding ultrasound propagation through bone is crucial for accurate assessment.
Bone strength depends on both bone mineral density and architectural structure.

Purpose of the Study:

To investigate the interaction between bone architecture, density, and ultrasound propagation.
To explore how these factors influence ultrasound velocity and frequency in bone.

Main Methods:

Utilized micro-computed tomography (micro-CT) to scan calcaneal trabecular bone samples.
Employed morphological image processing to create 15 distinct 3-D and 2-D bone datasets.
Performed computer simulations of ultrasound propagation through these 2-D bone slices.

Related Experiment Videos

Main Results:

Ultrasound propagation through bone is significantly affected by both bone density and architectural features.
A direct linear correlation between structural anisotropy and ultrasound measurements was not observed.
Simulations revealed complex interactions influencing ultrasonic velocity and waveform frequency.

Conclusions:

Both bone density and architecture are critical factors in ultrasound wave propagation.
Computational methods are powerful tools for studying ultrasound in bone and tissue characterization.
Further research is needed to fully elucidate the relationship between bone properties and ultrasound behavior.