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Nonlinearity parameter for tissue-mimicking materials.

F Dong1, E L Madsen, M C MacDonald

  • 1Department of Medical Physics, University of Wisconsin-Madison, 53706, USA.

Ultrasound in Medicine & Biology
|July 22, 1999
PubMed
Summary
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Ultrasonic nonlinearity parameter B/A was measured for tissue-mimicking materials. Nonfat materials showed values similar to soft tissues, while fat materials reflected typical ranges for fatty tissues.

Area of Science:

  • Medical Physics
  • Acoustics
  • Biomaterials

Background:

  • Accurate characterization of tissue-mimicking materials is crucial for ultrasound research.
  • The ultrasonic nonlinearity parameter (B/A) is a key material property influencing wave propagation.

Purpose of the Study:

  • To determine the ultrasonic nonlinearity parameter B/A for various tissue-mimicking materials.
  • To assess the suitability of these materials for ultrasound applications.

Main Methods:

  • A finite amplitude insert-substitution method was employed.
  • The amplitudes of the second harmonic were measured in degassed distilled water and the samples.
  • The ratio of second harmonic amplitudes was used to calculate the B/A parameter.

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Main Results:

  • Nonfat tissue-mimicking materials exhibited B/A values ranging from 5.6 to 6.6, comparable to soft tissues.
  • Fat tissue-mimicking materials showed B/A values of 9.8 and 11.1, aligning with typical fatty tissue ranges.
  • Measurements for corn oil and ethylene glycol agreed with published data.

Conclusions:

  • The studied nonfat materials effectively mimic the ultrasonic nonlinearity of soft tissues.
  • The studied fat materials represent the lower and upper bounds of B/A for fatty tissues.
  • The finite amplitude insert-substitution method provides reliable B/A measurements for tissue-mimicking materials.