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Related Experiment Videos

Optic disc elevation in Down syndrome.

A I Al-Hemidan1, S A Al-Hazzaa, P Chavis

  • 1Department of Ophthalmology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Ophthalmic Genetics
|July 23, 1999
PubMed
Summary
This summary is machine-generated.

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Optic disc elevation in Down syndrome patients may not indicate serious intracranial issues. Clinical follow-up and fluorescein angiography are often sufficient for diagnosis.

Area of Science:

  • Ophthalmology
  • Neurology
  • Genetics

Background:

  • Optic disc elevation in Down syndrome is rare.
  • It can mimic intracranial space-occupying lesions.
  • Requires careful differential diagnosis.

Observation:

  • Four Down syndrome patients with optic disc elevation were studied.
  • No intracranial pathology was found in these cases.
  • Ophthalmological and neuroradiological evaluations were conducted.

Findings:

  • Three patients had mild hyperopia; one had myopia.
  • Optic disc elevation was the primary ocular finding.
  • Absence of intracranial lesions confirmed by investigations.

Implications:

Related Experiment Videos

  • Disc elevation in Down syndrome may be benign.
  • Fluorescein angiography can aid diagnosis.
  • Clinical monitoring may suffice, avoiding invasive tests.