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Plasma agmatine and platelet imidazoline receptors in depression
1Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson 39216-4505, USA. AHalaris@psychiatry.umsmed.edu
Annals of the New York Academy of Sciences
|July 23, 1999
Abstract:
Plasma agmatine concentrations are elevated significantly in depressed patients compared to healthy controls. Treatment with the antidepressant bupropion normalized plasma agmatine levels. Correlational evidence is presented that a change in plasma agmatine levels may lead to similar changes in platelet I1 imidazoline receptors.