Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Blindness from bad bones.

R M Siatkowski1, N F Vilar, L Sternau

  • 1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Florida, USA.

Survey of Ophthalmology
|July 23, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of topoisomerase I and II expression in primary brain tumor and lung cancer.

Oncology reports·2011
Same author

Preschool vision screening using the MTI-Photoscreener.

Pediatric nursing·2002
Same author

Optic neuropathy and chiasmopathy in the diagnosis of systemic lupus erythematosus.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2001
Same author

Grand rounds #63: a case of a bilateral gaze limitation with diplopia for reading after two surgical procedures to treat a right medical rectus muscle paresis.

Binocular vision & strabismus quarterly·2001
Same author

Long-term visual outcome in patients with anterior visual pathway gliomas.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2001
Same author

Neuroma as a cause of oculomotor palsy in infancy and early childhood.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2001
Same journal

Macular telangiectasia masqueraders.

Survey of ophthalmology·2026
Same journal

Utilization of anterior segment optical coherence tomography in childhood glaucoma: A systematic review.

Survey of ophthalmology·2026
Same journal

Peripapillary pachychoroid syndrome: Clinical and imaging features, diagnostic differentiation and therapeutic strategies.

Survey of ophthalmology·2026
Same journal

Prognostic factors and postoperative outcomes in pediatric cataract patients: A systematic review and meta-analysis.

Survey of ophthalmology·2026
Same journal

Predicting the progression of proliferative diabetic retinopathy: Pathophysiology, imaging phenotypes, and determinants of disease persistence despite therapy.

Survey of ophthalmology·2026
Same journal

Comment on "Quantitative imaging for assessing uveitis activity: A comprehensive review".

Survey of ophthalmology·2026
See all related articles

Osteopetrosis can cause vision loss through various mechanisms. In this case, optic nerve compression was ruled out, highlighting jugular foramen obstruction as a cause of increased intracranial pressure and visual impairment.

Area of Science:

  • Neurology
  • Ophthalmology
  • Genetics

Background:

  • Osteopetrosis is a rare genetic disorder characterized by impaired osteoclast function, leading to bone defects.
  • Progressive visual loss is a common neurological complication in osteopetrosis patients.

Observation:

  • A child with osteopetrosis presented with progressive visual loss.
  • Computed tomography and digital holography confirmed patent optic canals, excluding optic nerve compression as the cause.

Findings:

  • The patient's visual loss was attributed to increased intracranial pressure.
  • This pressure resulted from obstruction of cerebral venous outflow at the jugular foramen.

Implications:

  • This case underscores the importance of evaluating skull base foramina in osteopetrosis patients with visual disturbances.

Related Experiment Videos

  • Identifying venous outflow obstruction is crucial for diagnosing and managing visual loss in osteopetrosis.