Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primate models to understand human aggression.

N H Kalin1

  • 1Department of Psychiatry, University of Wisconsin, Madison 53719-1179, USA.

The Journal of Clinical Psychiatry
|July 27, 1999
PubMed
Summary

Studies in rhesus monkeys reveal distinct biological mechanisms for defensive and offensive aggression. Environmental factors and early life experiences significantly influence aggressive behaviors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidental Findings from 16,400 Brain MRI Examinations of Research Volunteers.

AJNR. American journal of neuroradiology·2023
Same author

Heightened extended amygdala metabolism following threat characterizes the early phenotypic risk to develop anxiety-related psychopathology.

Molecular psychiatry·2016
Same author

Extreme early-life anxiety is associated with an evolutionarily conserved reduction in the strength of intrinsic functional connectivity between the dorsolateral prefrontal cortex and the central nucleus of the amygdala.

Molecular psychiatry·2014
Same author

Evolutionarily conserved prefrontal-amygdalar dysfunction in early-life anxiety.

Molecular psychiatry·2014
Same author

CRHR1 genotypes, neural circuits and the diathesis for anxiety and depression.

Molecular psychiatry·2012
Same author

Anxiety-related behavioral inhibition in rats: a model to examine mechanisms underlying the risk to develop stress-related psychopathology.

Genes, brain, and behavior·2010

Area of Science:

  • Neuroscience
  • Primate Behavior
  • Behavioral Biology

Background:

  • Primate studies offer models for clinical aggression.
  • Understanding the biological underpinnings of aggression requires further investigation.

Purpose of the Study:

  • To explore the biological mechanisms of aggressive behaviors in rhesus monkeys.
  • To differentiate the neural correlates of defensive versus offensive aggression.

Main Methods:

  • Analysis of aggressive behaviors in rhesus monkeys.
  • Correlation of behavioral types with neurobiological markers (e.g., brain activity, hormone levels).

Main Results:

  • Defensive aggression linked to fear, right frontal brain activity, and high cortisol.
  • Offensive/impulsive aggression associated with low serotonin, high testosterone, and low cortisol.
  • Environmental factors and mother-infant relationship disruptions modulate aggression.

Conclusions:

  • Rhesus monkey aggression models highlight distinct neurobiological pathways for different aggression types.
  • Early life environment critically influences the development and expression of aggression.

Related Experiment Videos