Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sentinel-node guided lymph-node dissection for merkel cell carcinoma.

N Wasserberg1, M Feinmesser, J Schachter

  • 1Departments of Surgery B, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|July 27, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phase II single-arm study of nivolumab and ipilimumab (Nivo/Ipi) in previously treated classical Kaposi sarcoma (cKS).

Annals of oncology : official journal of the European Society for Medical Oncology·2022
Same author

Repetitive antidotal treatment is crucial in eliminating eye pathology, respiratory toxicity and death following whole-body VX vapor exposure in freely moving rats.

Archives of toxicology·2019
Same author

Paediatric primary cutaneous marginal zone B-cell lymphoma: does it differ from its adult counterpart?

The British journal of dermatology·2016
Same author

Unilesional folliculotropic mycosis fungoides: a unique variant of cutaneous lymphoma.

Journal of the European Academy of Dermatology and Venereology : JEADV·2014
Same author

Does mca contribute to the follow-up of breast-cancer patients by ca-15-3.

International journal of oncology·2011
Same author

Amplification of the expression of major histocompatibility class-I antigens by inducers of differentiation and gamma interferon in murine and human solid tumor-cell lines.

International journal of oncology·2011
Same journal

AI-powered real-time detection and classification of peritoneal nodules in colorectal cancer using multi-center laparoscopic data: A feasibility study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same journal

Advances in intraoperative margin assessment for solid tumors: Toward a new era of personalized precision surgery.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same journal

Refining oncological resectability for intrahepatic cholangiocarcinoma: Radiological assessment of mediastinal lymph node enlargement does not reflect clinical prognosis after curative resection.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same journal

Macroscopic venous tumour thrombus in paediatric adrenocortical tumours.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same journal

Outcomes after pulmonary bilobectomy for NSCLC: The role of surgical type, indication, and pulmonary function.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same journal

Impact of 18-FDG PET-CT on the preoperative staging and management of Incidental Gall Bladder Cancer (IGBC)- A prospective study from a tertiary care centre in North India.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
See all related articles

Sentinel lymph node biopsy, a technique used for melanoma, is applicable for Merkel cell carcinoma treatment. This method accurately identifies metastatic lymph nodes, guiding surgical dissection for this aggressive skin cancer.

Area of Science:

  • Oncology
  • Dermatology
  • Surgical Oncology

Background:

  • Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin tumor with unpredictable behavior, similar to malignant melanoma.
  • Both MCC and melanoma exhibit early lymph node involvement, distant metastases, and high recurrence rates, making treatment challenging.
  • Current treatment strategies for MCC remain debated, necessitating innovative approaches.

Observation:

  • A 60-year-old male patient with MCC on the right buttock underwent sentinel lymph node biopsy.
  • Pre-operative lymphoscintigraphy and intraoperative lymph-node mapping were employed, adapting melanoma treatment techniques.
  • A metastatic first-order sentinel node was identified via frozen section analysis.

Findings:

  • Radical right groin dissection was performed following the identification of a metastatic sentinel node.

Related Experiment Videos

  • All other lymph nodes in the basin, including the second-order sentinel node and Cloquet node, were disease-free.
  • The patient is currently receiving adjuvant chemotherapy and radiotherapy.

    • Implications:

    • Sentinel lymph node biopsy is a feasible and applicable technique for staging and guiding treatment in Merkel cell carcinoma.
    • This approach may improve the accuracy of lymph node assessment and potentially optimize surgical management for MCC.
    • Further studies are warranted to validate the efficacy and long-term outcomes of sentinel lymph node biopsy in MCC patients.