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The development and therapeutic potential of protein kinase inhibitors
1MRC Protein Phosphorylation Unit, Department of Biochemistry, MSI/WTB Complex, Dow Street, University of Dundee, Dundee, DD1 5EH, Scotland, UK. pcohen@bad.dundee.ac.uk
Current Opinion in Chemical Biology
|July 27, 1999
Abstract:
A number of small cell-permeant protein kinase inhibitors have been developed that have the potential for treating a variety of diseases. The basis for the specificity of several of these drugs has been elucidated and a number are undergoing human clinical trials.