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Clinical and morphologic features of hypertrophic cardiomyopathy in elderly patients 85 years or older

Z Y Lai1, C M Shih, N C Chang

  • 1Department of Medicine, Taipei Medical College and Hospital, Taiwan.

Japanese Heart Journal
|July 27, 1999
PubMed

Insights

Elderly patients with hypertrophic cardiomyopathy (HC) exhibit unique left ventricular (LV) morphology, characterized by basal septal bulging and anterior hypertrophy. Advanced age and mild hypertension appear to influence this distinctive geometry in older individuals.

Area of Science:

  • Cardiology
  • Geriatrics
  • Medical Imaging

Background:

  • Hypertrophic cardiomyopathy (HC) is a complex cardiac condition.
  • Distinctive left ventricular (LV) morphology in elderly patients with HC requires further investigation.
  • The influence of advanced age and hypertension on HC morphology is not fully understood.

Purpose of the Study:

  • To investigate the unique left ventricular (LV) morphology in elderly patients (>= 85 years) with hypertrophic cardiomyopathy (HC).
  • To explore the relationship between advanced age, mild hypertension, and the characteristic LV geometry in this population.

Main Methods:

  • Comparative study of 14 elderly HC patients (>= 85 years) and 45 young HC patients (<= 40 years).
  • Clinical data collection including age, hypertension status, and syncope occurrence.
  • Echocardiographic assessment of LV wall thickness, septal bulging, and hypertrophy patterns.

Main Results:

  • Elderly patients presented with milder LV wall thickening (18 +/- 4 mm vs 25 +/- 8 mm) compared to younger patients.
  • A significantly higher prevalence of basal septal bulging (86% vs 0%) and anterior septal hypertrophy (79% vs 0%) was observed in the elderly group.
  • Mild hypertension was prevalent in 71% of elderly patients and correlated with basal septal bulging and anterior septal hypertrophy.

Conclusions:

  • Elderly patients (>= 85 years) with HC display a striking and distinct left ventricular (LV) morphology.
  • Advanced age and mild hypertension are likely contributing factors to the unique geometry observed in elderly HC patients.

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